Withdrawal symptoms occur in infants born to mothers who get barbiturates through the final trimester of pregnancy
Induction of microsomal enzymes by this drug, may possibly shorten the fifty percent-life of doxycycline for so long as two months soon after barbiturate therapy discontinued; observe clinical reaction to doxycycline intently if both medicines administered concurrently
pentobarbital will increase toxicity of methoxyflurane by expanding metabolism. Contraindicated. Improved metabolism of methoxyflurane to nephrotoxic compounds.
pentobarbital will reduce the extent or effect of aprepitant by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.
pentobarbital will lower the level or result of theophylline by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.
pentobarbital will reduce the extent or influence of etravirine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.
Warning when discontinuing CYP3A4 inducers which have been coadministered with hydrocodone; plasma concentrations of hydrocodone may perhaps maximize and may lead to probably deadly respiratory depression
pentobarbital decreases levels of elvitegravir/cobicistat/emtricitabine/tenofovir DF by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Might bring on lack of virologic reaction and feasible resistance.
pentobarbital will reduce the extent or effect of levamlodipine by influencing hepatic/intestinal enzyme CYP3A4 metabolism.
Comment: Barbiturates may possibly increase adverse consequences, including respiratory melancholy, made by poisonous doses of TCAs. With therapeutic doses of TCAs, barbiturates enhance metabolism and reduce blood concentrations of TCAs.
pentobarbital will reduce the extent or impact of buprenorphine buccal by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.
pentobarbital will lessen the level or influence of diazepam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.
pentobarbital improves toxicity of ifosfamide by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe. CYP3A4 inducers could enhance the metabolism of ifosfamide to nembutal kaufen its Lively alkylating metabolites.
pentobarbital will lower the extent or effect of irinotecan liposomal by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.